JMSSJ On-line

JMSSJ On-line, Vol. 42 (1994) No. 2, pp. 95-103

A New Approach to Accurate Mass Measurement by Field Desorption Peak Matching		>> Full Text PDF >> References
*Masayoshi KUBO,^a) Kazuaki KANO,^a) Koji HAYASHI,^a) Masao MARUNO,^a) Philip IRELAND,^b) and Takehiro TAKEDA^c)** ^a) Tsumura Central Research Laboratories (3586 Ami-machi, Yoshiwara, Inashiki-gun, Ibaraki 300-11, Japan) ^b) Kratos Analytical (Barton Dock Road, Urmston, Manchester M31 2LD, England UK) ^c) Shimadzu Corp.* (1-Nishinokyo-Kuwabaracho, Nakagyo-ku, Kyoto 604, Japan)

Despite the standard ionization techniqus. EI, CI, FAB, etc., there is still a continuing analytical utility for Field Desorption (FD) for certain classes of compounds. Therefore, the method of accurate mass measurement by FD Peak Matching was investigated. Recent advances in instrument control and data acquisition/processing (post-acquisition data processing) with the engineering workstation have enabled accurate mass measurement to become a viable option for routine analysis. Molecular masses of thirteen standard compounds were measured by the FD Peak Matching to illustrate the applicability of this method. Generally, both sample and reference, PEG400 or PEG600, were loaded onto the same emitter. The possibility of using separate emitters for sample and reference was also explored. The accuracy obtained was comparable to other routine methods (e.g., EI, FAB). Six important factors which enable accurate mass measurement to be done on a routine basis were elucidated by this investigation.

Key words: FD, Accurate mass measurement, Peak Matching, Post-acquisition, Emitter, Reference ion

[ Full Text PDF ] [ References ]