JMSSJ On-line, Vol. 43 (1995) No. 1, pp. 85-96
Some Characteristics of Gas-Phase Fast Atom Bombardment Ionization Mass Spectrometry: Chromium Hexacarbonyl and Trolox
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    Toshihide NISHIMURA and Mitsuo TAKAYAMA*

    Upjohn Pharmaceuticals Limited, Tsukuba Research Laboratories (23 Wadai, Tsukuba-shi, Ibaraki 300-42, Japan) * Faculty of Pharmaceutical Sciences, Toho University (2-2-1 Miyama, Funabashi, Chiba 274, Japan)

Gas-phase fast atom bombardment (GFAB) mass spectra of the chromium hexacarbonyl molecule were compared with its charge-exchange ionization (CEI) mass spectra. It was found that the fragmentation pattern of chromium hexacarbonyl ions obtained by He-CEI mass spectrometry most resembles those measured in GFAB, and so it seems that energy deposition during GFAB implies involvement of a resonance-like energy transfer from fast atoms and may be similar or higher than that in He-CEI reaction. No great difference was observed in GFAB mass spectrum for a variety of fast bombarding particles including He, Ar, Xe, Cs, and isobutane. A high pressure GFAB mass spectrum of trolox measured using a Cs beam demonstrated its reactive nature that exchange reaction between hydroxy protons and Cs+ ions seems to take place in gas phase for the molecule and its neutral fragments while a Cs-FAB mass spectrum measured under a relatively low sample gas pressure showed only a fragmentation pattern characterized by a high abundance of fragment ions. Since Cs is only an alkali metal among fast bombarding particles, its chemical nature may be responsible for the observed reactivity with the target molecule.

Key words: Gas-phase fast atom bombardment mass spectrometry, Matrix-assisted fast bombardment mass spectrometry, Charge-exchange ionization mass spectrometry, Rydberg atoms, Collisional ionization

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