JMSSJ On-line

JMSSJ On-line, Vol. 48 (2000) No. 5, pp. 353-356

ESI-MS Analysis of Effluents from Medical Silicon Rubber		>> Full Text PDF >> References
*Tsuyoshi FUKUO^a), Naoko KUBOTA^a), Masahiro TAMURA^b), and Ryuichi ARAKAWA^a)** ^† This paper is dedicated to the memory of the late Professor Takekiyo MATSUO. ^a) Department of Applied Chemistry, Kansai University (Yamate-cho, Suita 564-8680, Japan)* ^b) Fuso Pharmaceutical Industry (Morinomiya, Jyoto-ku, Osaka 536-0025, Japan)

The catheter tubes of medical silicon rubber were dipped in ethanol. The effluents were fractionated by thin-layer chromatography (TLC), and their fractions were analyzed by ion trap electrospray ionization mass spectrometry (ESI-MS). The ESI mass spectra resulting from the main TLC fraction, R₁=0.5 showed that the effluents were determined to be poly(dimethyl siloxane) (8 to 20 mer) that is a main part of a silicon rubber. The spectra for the origin in TLC showed that poly(ethylene glycol) (4 to 10 mer and 14 to 18 mer) and poly- (propylene glycol) (19 to 36 mer) as an antistatic agent were identified.

Key words: Medical plastics, Silicon rubber, Catheters, Effluents, Electrospray ionization mass spectrometry (ESI-MS), Poly(dimethyl siloxane), Poly(ethylene glycol), Poly(propylene glycol)