JMSSJ On-line

JMSSJ On-line, Vol. 51 (2003) No. 1, pp. 242-246

Elimination Processes of Guest Molecules from the Inclusion Compounds of Deoxycholic Acid^†		>> Full Text PDF >> References
*Takayoshi KIMURA,^a) Yuichi KASAI,^a) Tomohide TSUJIMOTO,^a) Emi KAWAMURA,^a) Tadashi KAMIYAMA,^a) and Hatsumi AKI^b)** ^*a)Department of Chemistry, Faculty of Science and Technology, Kinki University (3-4-1 Kowakae, Higashi-Osaka 577-8502, Japan) E-mail: kimura@chem.kindai.ac.jp ^b)Faculty of Pharmaceutical Science, Fukuoka University (8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan)

Thermal behaviors of the inclusion compounds of deoxycholic acid with methanol, ethanol, propane-1-ol, propane-2-ol, and butane-1-ol have been studied by TG-DTA-MS and DSC. Liberation processes of guest molecules from their inclusion compounds of methanol, ethanol were carried out in a single step. Those of propanols and butane-1-ol from the corresponding inclusion compounds proceed in complicated steps. The elimination temperatures, enthalpies and the activation enthalpies of eliminations have been determined by TG, DSC, and MS.

Key words: Inclusion compound, Deoxycholic acid, Methanol, Ethanol, Propane-1-ol, Propane-2-ol, Butane-1-ol, Activation energy of elimination