JMSSJ On-line

JMSSJ On-line, Vol. 56 (2008) No. 6, pp. 263-268

Why Can Reflectron Mode in Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry Perform MS/MS-like Analysis?		>> Full Text PDF >> References
Koichi TANAKA,¹ Ken-ichi YOSHINO,^{2, 3} Tomoya KINUMI,⁴ and Mitsuo TAKAYAMA⁵ ¹ Koichi Tanaka Mass Spectrometry Research Laboratory, Shimadzu Corporation, Kyoto, JAPAN ² Biosignal Research Center, Organization of Advanced Science and Technology, and ³ The Integrated Center for Mass Spectrometry, Graduate School of Medicine, Kobe University, Kobe, JAPAN ⁴ National Institute of Advanced Industrial Science and Technology (AIST), National Metrology Institute of Japan (NMIJ), Organic Analytical Chemistry Division, Bio-Medical Standard Section, Tsukuba, IBARAKI, JAPAN ⁵ Mass Spectrometry Laboratory, International Graduate School of Arts and Sciences, Yokohama City University, Yokohama, JAPAN

By measurement of post-source decay (PSD) product ion mass spectrum, matrix-assisted laser desorption/ionization (MALDI) time-of-flight mass spectrometry (TOFMS) enable mass spectrometry/mass spectrometry (MS/MS)-like analysis to obtain structural information. We will explain the basics of MS/MS-like analysis in reflectron mode of MALDI TOFMS by comparing post-source decay product ion mass spectrum acquired by the standard reflectron and the curved field reflectron.

Key words: Post-source decay, Time-of-flight mass spectrometer, Matrix-assisted laser desorption/ionization, Curved field reflectron