| Principles of the Delayed Extraction Technique |
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1 Koichi Tanaka Mass Spectrometry Research Laboratory, Shimadzu Corporation, Kyoto, JAPAN 2 Advanced Technology Division, JEOL Ltd., Akishima, TOKYO, JAPAN 3Biosignal Research Center, Organization of Advanced Science and Technology, and 4The Integrated Center for Mass Spectrometry, Graduate School of Medicine, Kobe University, Kobe, JAPAN |
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| The delayed extraction (also known as pulsed extraction) technique involves the application of a time delay between the ionization pulse and an accelerating voltage pulse for desorption/ionization from a surface. This technique can achieve energy focusing in a matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) mass spectrometer and is used to improve mass resolving power. We explain the principles of delayed extraction (pulsed extraction) used in a MALDI TOF mass spectrometer. | ||
| Key words: Delayed extraction, Pulsed extraction, Time-of-flight mass spectrometer, Matrix-assisted laser desorption/ionization | ||
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