JMSSJ On-line, Vol. 57 (2009) No. 3, pp. 183-186

Metabolome Analysis of Colon Tumor Tissues by Capillary Electrophoresis Time-of-Flight Mass Spectrometer		>> Full Text PDF >> References
Akiyoshi HIRAYAMA,1 Kenjiro KAMI,1 Masahiro SUGIMOTO,1 Masaru TOMITA,1 Hiroyasu ESUMI,2 and Tomoyoshi SOGA1 1 Institute for Advanced Biosciences, Keio University, Tsuruoka, YAMAGATA, JAPAN 2 National Cancer Center Hospital East, Kashiwa, CHIBA, JAPAN
Capillary electrophoresis-mass spectrometry based metabolomics exhibits unlimited potentials to elucidate global metabolic profiles of various types of samples including clinical tissues. In addition, non-targeted metabolome analysis by this method holds the promise of discovering novel biomarker candidates. In this commentary, we introduce our strategies for studying cancer-specific metabolism by analyzing metabolome of surgically excised tumor tissues．
Key words: Metabolomics, Capillary electrophoresis-mass spectrometry, Energy metabolism, Biomarker discovery

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